Luigi Manenti Selected Research

imgatuzumab

2/2014	Open-label, multicentre expansion cohort to evaluate imgatuzumab in pre-treated patients with KRAS-mutant advanced colorectal carcinoma.
10/2011	Phase I pharmacokinetic and pharmacodynamic dose-escalation study of RG7160 (GA201), the first glycoengineered monoclonal antibody against the epidermal growth factor receptor, in patients with advanced solid tumors.

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Luigi Manenti Research Topics

Disease

6	Neoplasms (Cancer) 12/2021 - 08/2003
4	Ascites 05/2005 - 08/2003
3	Fatigue 01/2022 - 01/2021
3	Carcinoma (Carcinomatosis) 05/2005 - 08/2003
2	Colorectal Neoplasms (Colorectal Cancer) 01/2021 - 02/2014
2	Hepatocellular Carcinoma (Hepatoma) 01/2019 - 01/2018
2	Ovarian Neoplasms (Ovarian Cancer) 05/2005 - 11/2004
1	Nausea 01/2022
1	Pneumonia (Pneumonitis) 01/2022
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2022
1	Nasopharyngeal Neoplasms (Cancer of the Nasopharynx) 12/2021
1	Pruritus (Itching) 12/2021
1	Diarrhea 01/2018

Drug/Important Bio-Agent (IBA)

3	spartalizumabIBA 01/2022 - 01/2021
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 05/2005 - 08/2003
2	Tyrosine Kinase InhibitorsIBA 01/2019 - 08/2003
2	imgatuzumabIBA 02/2014 - 10/2011
1	Adenosine (Adenocard)FDA LinkGeneric 01/2022
1	Alanine (L-Alanine)FDA Link 01/2022
1	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2022
1	SteroidsIBA 01/2022
1	PlatinumIBA 12/2021
1	RNA (Ribonucleic Acid)IBA 12/2021
1	sabatolimabIBA 01/2021
1	capmatinibIBA 01/2019
1	Biomarkers (Surrogate Marker)IBA 01/2019
1	CholesterolIBA 01/2018
1	roblitinibIBA 01/2018
1	7 alpha-hydroxy-4-cholesten-3-oneIBA 01/2018
1	Phosphotransferases (Kinase)IBA 01/2018
1	Monoclonal AntibodiesIBA 10/2011
1	ErbB Receptors (EGF Receptor)IBA 10/2011
1	Cisplatin (Platino)FDA LinkGeneric 05/2005
1	Neoplasm Antigens (Tumor Antigens)IBA 11/2004
1	AntibodiesIBA 11/2004
1	Peptides (Polypeptides)IBA 11/2004
1	Proteins (Proteins, Gene)FDA Link 11/2004
1	LigandsIBA 11/2004
1	Matrix Metalloproteinases (MMPs)IBA 09/2003
1	Metalloproteases (Metalloproteinases)IBA 09/2003
1	Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA 08/2003
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 08/2003
1	Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA 08/2003
1	orantinib (SU6668)IBA 08/2003
1	Type 1 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 1)IBA 08/2003
1	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 08/2003
1	Biological ProductsIBA 08/2003
1	Paclitaxel (Taxol)FDA LinkGeneric 08/2003

Therapy/Procedure

3	Therapeutics 05/2005 - 08/2003
1	Drug Therapy (Chemotherapy) 12/2021
1	Oral Administration 01/2018